Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo

Activation of the NLRP3 inflammasome results in caspase 1 cleavage, which subsequently leads to IL-1β and IL-18 secretion, as well as pyroptosis, and aberrant activation of the inflammasome is involved in several diseases such as type 2 diabetes, atherosclerosis, multiple sclerosis, Parkinson's...

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Main Authors: Xiangxi Kong (Author), Yajin Liao (Author), Lujun Zhou (Author), Ying Zhang (Author), Jinbo Cheng (Author), Zengqiang Yuan (Author), Shukun Wang (Author)
Format: Book
Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
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3rd Floor Main Library

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