Hematopoietic Cell Kinase (HCK) Is Essential for NLRP3 Inflammasome Activation and Lipopolysaccharide-Induced Inflammatory Response In Vivo

• Asıl Yazarlar: Xiangxi Kong (Yazar), Yajin Liao (Yazar), Lujun Zhou (Yazar), Ying Zhang (Yazar), Jinbo Cheng (Yazar), Zengqiang Yuan (Yazar), Shukun Wang (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Activation of the NLRP3 inflammasome results in caspase 1 cleavage, which subsequently leads to IL-1β and IL-18 secretion, as well as pyroptosis, and aberrant activation of the inflammasome is involved in several diseases such as type 2 diabetes, atherosclerosis, multiple sclerosis, Parkinson's...