Glucocappasalin Induces G2/M-Phase Arrest, Apoptosis, and Autophagy Pathways by Targeting CDK1 and PLK1 in Cervical Carcinoma Cells

• Glavni autori: Guangya Xu (Autor), Xueling Yan (Autor), Zhongjia Hu (Autor), Lulu Zheng (Autor), Ke Ding (Autor), Yamei Zhang (Autor), Yi Qing (Autor), Tao Liu (Autor), Lijia Cheng (Autor), Zheng Shi (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Glucocappasalin (GCP), a natural product derived from the seeds of Descurainia sophia (L.) Webb. ex Prantl, exhibits potential antitumor activity in HeLa cervical carcinoma cells. In this study, we investigated the anti-cervical cancer property of GCP through the induction of cell cycle arrest, apop...