Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR

• প্রধান লেখক: Neeraj Kumar (Author), Subba Rao Devineni (Author), Prasad Reddy Gajjala (Author), Shailendra Kumar Dubey (Author), Pramod Kumar (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2017-12-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

One unknown impurity (Imp-II) during the analysis of laboratory batches of isoproterenol hydrochloride was detected in the level ranging from 0.04% to 0.12% by high performance liquid chromatography with UV detection. The unknown impurity structure was proposed as 4-[2-(propan-2-ylamino)ethyl]benzen...