Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR

• Asıl Yazarlar: Neeraj Kumar (Yazar), Subba Rao Devineni (Yazar), Prasad Reddy Gajjala (Yazar), Shailendra Kumar Dubey (Yazar), Pramod Kumar (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2017-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

One unknown impurity (Imp-II) during the analysis of laboratory batches of isoproterenol hydrochloride was detected in the level ranging from 0.04% to 0.12% by high performance liquid chromatography with UV detection. The unknown impurity structure was proposed as 4-[2-(propan-2-ylamino)ethyl]benzen...