A Combined Drug Treatment That Reduces Mitochondrial Iron and Reactive Oxygen Levels Recovers Insulin Secretion in NAF-1-Deficient Pancreatic Cells

A Combined Drug Treatment That Reduces Mitochondrial Iron and Reactive Oxygen Levels Recovers Insulin Secretion in NAF-1-Deficient Pancreatic Cells

Decreased insulin secretion, associated with pancreatic β-cell failure, plays a critical role in many human diseases including diabetes, obesity, and cancer. While numerous studies linked β-cell failure with enhanced levels of reactive oxygen species (ROS), the development of diabetes associated wit...

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Main Authors: Ola Karmi (Author), Yang-Sung Sohn (Author), Henri-Baptiste Marjault (Author), Tal Israeli (Author), Gil Leibowitz (Author), Konstantinos Ioannidis (Author), Yaakov Nahmias (Author), Ron Mittler (Author), Ioav Z. Cabantchik (Author), Rachel Nechushtai (Author)
Format: Book
Published: MDPI AG, 2021-07-01T00:00:00Z.
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3rd Floor Main Library

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