Solubility enhancement, physicochemical characterization and formulation of fast-dissolving tablet of nifedipine-betacyclodextrin complexes

• প্রধান লেখক: Swati Changdeo Jagdale (লেখক), Vinayak Narhari Jadhav (লেখক), Aniruddha Rajaram Chabukswar (লেখক), Bhanudas Shankar Kuchekar (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Universidade de São Paulo, 2012-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The main objective of the study was to enhance the dissolution of nifedipine, a poorly water soluble drug by betacyclodextrin complexation and to study the effect of the preparation method on the in vitro dissolution profile. The stoichiometric ratio determined by phase solubility analysis for inclu...