Model‐Informed Dosing of Venetoclax in Healthy Subjects: An Exposure−Response Analysis

• প্রধান লেখক: Nimita Dave (লেখক), Sathej Gopalakrishnan (লেখক), Sven Mensing (লেখক), Ahmed Hamed Salem (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2019-11-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Venetoclax is an approved drug for the treatment of some hematological malignancies. Venetoclax can cause reduction in B‐lymphocyte counts as an on‐target effect. The purpose of this analysis is to quantify the relationship between venetoclax exposure and B‐lymphocyte levels to inform dosing of vene...