Multi-Drug-Resistant Cells Enriched From Chronic Myeloid Leukemia Cells by Doxorubicin Possess Tumor-Initiating-Cell Properties

• Главные авторы: Hong Xin (Автор), Ying Kong (Автор), Xiaoxiao Jiang (Автор), Ke Wang (Автор), Xiaoran Qin (Автор), Ze-Hong Miao (Автор), Yizhun Zhu (Автор), Wenfu Tan (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2013-01-01T00:00:00Z.
• Предметы: article
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Multiple drug resistance (MDR) occurring during chemotherapy is a major obstacle for treatment of cancers using chemotherapeutic drugs; thus, the mechanisms underlying MDR have attracted intensive attention. Many studies have shown that tumor-initiating cells exhibit a chemotherapeutic tolerance cha...