Multi-Drug-Resistant Cells Enriched From Chronic Myeloid Leukemia Cells by Doxorubicin Possess Tumor-Initiating-Cell Properties

• Main Authors: Hong Xin (Author), Ying Kong (Author), Xiaoxiao Jiang (Author), Ke Wang (Author), Xiaoran Qin (Author), Ze-Hong Miao (Author), Yizhun Zhu (Author), Wenfu Tan (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiple drug resistance (MDR) occurring during chemotherapy is a major obstacle for treatment of cancers using chemotherapeutic drugs; thus, the mechanisms underlying MDR have attracted intensive attention. Many studies have shown that tumor-initiating cells exhibit a chemotherapeutic tolerance cha...