Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

• मुख्य लेखकों: Adriana Cortés (लेखक), Maite Solas (लेखक), Álvaro Pejenaute (लेखक), Miguel A. Abellanas (लेखक), Marcos Garcia-Lacarte (लेखक), Maria S. Aymerich (लेखक), Javier Marqués (लेखक), María J. Ramírez (लेखक), Guillermo Zalba (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process. NADPH oxidases (NOX) are involved in oxidative stress-mediated vascular dysfunction and participate in the pathophys...