Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

• Váldodahkkit: Adriana Cortés (Dahkki), Maite Solas (Dahkki), Álvaro Pejenaute (Dahkki), Miguel A. Abellanas (Dahkki), Marcos Garcia-Lacarte (Dahkki), Maria S. Aymerich (Dahkki), Javier Marqués (Dahkki), María J. Ramírez (Dahkki), Guillermo Zalba (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2021-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process. NADPH oxidases (NOX) are involved in oxidative stress-mediated vascular dysfunction and participate in the pathophys...