Expression of Endothelial NOX5 Alters the Integrity of the Blood-Brain Barrier and Causes Loss of Memory in Aging Mice

• Glavni autori: Adriana Cortés (Autor), Maite Solas (Autor), Álvaro Pejenaute (Autor), Miguel A. Abellanas (Autor), Marcos Garcia-Lacarte (Autor), Maria S. Aymerich (Autor), Javier Marqués (Autor), María J. Ramírez (Autor), Guillermo Zalba (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Blood-Brain barrier (BBB) disruption is a hallmark of central nervous system (CNS) dysfunction, and oxidative stress is one of the molecular mechanisms that may underlie this process. NADPH oxidases (NOX) are involved in oxidative stress-mediated vascular dysfunction and participate in the pathophys...