Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

• Principais autores: Liang Wang (Autor), Yuntao Feng (Autor), Jianwen Wang (Autor), Tenglong Luo (Autor), Xinyue Wang (Autor), Mengze Wu (Autor), Runxia Wang (Autor), Dapeng Chen (Autor), Jiyan Li (Autor), Jingyu Wang (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic. Based on docking studies, arbutin, a natural product extracted from a traditional medicinal plant bearberry, was foun...