Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

• Main Authors: Liang Wang (Author), Yuntao Feng (Author), Jianwen Wang (Author), Tenglong Luo (Author), Xinyue Wang (Author), Mengze Wu (Author), Runxia Wang (Author), Dapeng Chen (Author), Jiyan Li (Author), Jingyu Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic. Based on docking studies, arbutin, a natural product extracted from a traditional medicinal plant bearberry, was foun...