Mouse models for preeclampsia: disruption of redox-regulated signaling

• Main Authors: Chambers Anne E (Author), Randeva Harpal (Author), Banerjee Subhasis (Author)
• Formato: Livro
• Publicado em: BMC, 2009-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<p>Abstract</p> <p>The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-O-methyl transferase (Comt-/-) in pregnant mice leads to human preeclampsia-like sym...