Mouse models for preeclampsia: disruption of redox-regulated signaling

• Ngā kaituhi matua: Chambers Anne E (Author), Randeva Harpal (Author), Banerjee Subhasis (Author)
• Hōputu: Pukapuka
• I whakaputaina: BMC, 2009-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

<p>Abstract</p> <p>The concept that oxidative stress contributes to the development of human preeclampsia has never been tested in genetically-defined animal models. Homozygous deletion of catechol-O-methyl transferase (Comt-/-) in pregnant mice leads to human preeclampsia-like sym...