piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice
SUMMARY The stable genomic integration and expression of a large transgene is a major hurdle in gene therapy. We show that the modified piggyBac (PB) transposon system can be used to introduce a 207 kb genomic DNA fragment containing the RORγ/γt locus into human cells and mice. PB-mediated transgene...
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| Materiálatiipa: | Girji |
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The Company of Biologists,
2013-05-01T00:00:00Z.
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A1234.567 |
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