Administration of a tropomyosin receptor kinase inhibitor attenuates sarcoma-induced nerve sprouting, neuroma formation and bone cancer pain

• Autori principali: Bloom Aaron P (Autore), Mantyh William G (Autore), Jimenez-Andrade Juan M (Autore), Freeman Katie T (Autore), Ghilardi Joseph R (Autore), Kuskowski Michael A (Autore), Mantyh Patrick W (Autore)
• Natura: Libro
• Pubblicazione: SAGE Publishing, 2010-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Pain often accompanies cancer and most current therapies for treating cancer pain have significant unwanted side effects. Targeting nerve growth factor (NGF) or its cognate receptor tropomyosin receptor kinase A (TrkA) has become an attractive target for attenuat...