Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection.

• Main Authors: Chandima Jeewandara (Author), Thiruni N Adikari (Author), Laksiri Gomes (Author), Samitha Fernando (Author), R H Fernando (Author), M K T Perera (Author), Dinuka Ariyaratne (Author), Achala Kamaladasa (Author), Maryam Salimi (Author), Shamini Prathapan (Author), Graham S Ogg (Author), Gathsaurie Neelika Malavige (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although antibody responses to dengue virus (DENV) in naturally infected individuals have been extensively studied, the functionality of DENV specific memory T cell responses in relation to clinical disease severity is incompletely understood.Using ex vivo IFNγ ELISpot assays, and by determining cyt...