Functionality of dengue virus specific memory T cell responses in individuals who were hospitalized or who had mild or subclinical dengue infection.

• Главные авторы: Chandima Jeewandara (Автор), Thiruni N Adikari (Автор), Laksiri Gomes (Автор), Samitha Fernando (Автор), R H Fernando (Автор), M K T Perera (Автор), Dinuka Ariyaratne (Автор), Achala Kamaladasa (Автор), Maryam Salimi (Автор), Shamini Prathapan (Автор), Graham S Ogg (Автор), Gathsaurie Neelika Malavige (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2015-04-01T00:00:00Z.
• Предметы: article
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Although antibody responses to dengue virus (DENV) in naturally infected individuals have been extensively studied, the functionality of DENV specific memory T cell responses in relation to clinical disease severity is incompletely understood.Using ex vivo IFNγ ELISpot assays, and by determining cyt...