Development and Optimization of Dipyridamole- and Roflumilast-Loaded Nanoemulsion and Nanoemulgel for Enhanced Skin Permeation: Formulation, Characterization, and In Vitro Assessment

• Main Authors: Zeyad Khalaf Maded (Author), Souad Sfar (Author), Ghada Abd Alrhman Taqa (Author), Mohamed Ali Lassoued (Author), Olfa Ben Hadj Ayed (Author), Hayder Adnan Fawzi (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study explores developing and optimizing a nanoemulsion (NE) system loaded with dipyridamole and roflumilast, aiming to improve skin penetration and retention. The NE formulation was further transformed into a nanoemulgel to enhance its application as a topical treatment for psoriasis. Solubili...