Development and Optimization of Dipyridamole- and Roflumilast-Loaded Nanoemulsion and Nanoemulgel for Enhanced Skin Permeation: Formulation, Characterization, and In Vitro Assessment

• Hoofdauteurs: Zeyad Khalaf Maded (Auteur), Souad Sfar (Auteur), Ghada Abd Alrhman Taqa (Auteur), Mohamed Ali Lassoued (Auteur), Olfa Ben Hadj Ayed (Auteur), Hayder Adnan Fawzi (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

This study explores developing and optimizing a nanoemulsion (NE) system loaded with dipyridamole and roflumilast, aiming to improve skin penetration and retention. The NE formulation was further transformed into a nanoemulgel to enhance its application as a topical treatment for psoriasis. Solubili...