Development and Optimization of Dipyridamole- and Roflumilast-Loaded Nanoemulsion and Nanoemulgel for Enhanced Skin Permeation: Formulation, Characterization, and In Vitro Assessment

• Главные авторы: Zeyad Khalaf Maded (Автор), Souad Sfar (Автор), Ghada Abd Alrhman Taqa (Автор), Mohamed Ali Lassoued (Автор), Olfa Ben Hadj Ayed (Автор), Hayder Adnan Fawzi (Автор)
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• Опубликовано: MDPI AG, 2024-06-01T00:00:00Z.
• Предметы: article
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This study explores developing and optimizing a nanoemulsion (NE) system loaded with dipyridamole and roflumilast, aiming to improve skin penetration and retention. The NE formulation was further transformed into a nanoemulgel to enhance its application as a topical treatment for psoriasis. Solubili...