Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
Abstract Five‐fluorouracil (5‐FU) is a chemotherapeutic agent that is mainly metabolized by the rate‐limiting enzyme dihydropyrimidine dehydrogenase (DPD). The DPD enzyme activity deficiency involves a wide range of severities. Previous studies have demonstrated the effect of a DPYD single nucleotid...
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Wiley,
2022-05-01T00:00:00Z.
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A1234.567 |
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