Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

ABSTRACTDelineating the precise regions on an antigen that are targeted by antibodies has become a key step for the development of antibody therapeutics. X-ray crystallography and cryogenic electron microscopy are considered the gold standard for providing precise information about these binding sit...

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主要な著者: Tiphanie Pruvost (著者), Magali Mathieu (著者), Steven Dubois (著者), Bernard Maillère (著者), Emmanuelle Vigne (著者), Hervé Nozach (著者)
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出版事項: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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