Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

ABSTRACTDelineating the precise regions on an antigen that are targeted by antibodies has become a key step for the development of antibody therapeutics. X-ray crystallography and cryogenic electron microscopy are considered the gold standard for providing precise information about these binding sit...

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Main Authors: Tiphanie Pruvost (Author), Magali Mathieu (Author), Steven Dubois (Author), Bernard Maillère (Author), Emmanuelle Vigne (Author), Hervé Nozach (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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