Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters

Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters

A set of 6- to 24-valent clusters was constructed with terminal deoxynojirimycin (DNJ) inhibitory heads through C6 or C9 linkers by way of Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions between mono- or trivalent azido-armed iminosugars and calix[8]arene scaffolds differing in their va...

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Main Authors: Jérémy P. Schneider (Author), Stefano Tommasone (Author), Paolo Della Sala (Author), Carmine Gaeta (Author), Carmen Talotta (Author), Céline Tarnus (Author), Placido Neri (Author), Anne Bodlenner (Author), Philippe Compain (Author)
Format: Book
Published: MDPI AG, 2020-11-01T00:00:00Z.
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