Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters

• Autores principales: Jérémy P. Schneider (Autor), Stefano Tommasone (Autor), Paolo Della Sala (Autor), Carmine Gaeta (Autor), Carmen Talotta (Autor), Céline Tarnus (Autor), Placido Neri (Autor), Anne Bodlenner (Autor), Philippe Compain (Autor)
• Formato: Libro
• Publicado: MDPI AG, 2020-11-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

A set of 6- to 24-valent clusters was constructed with terminal deoxynojirimycin (DNJ) inhibitory heads through C6 or C9 linkers by way of Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions between mono- or trivalent azido-armed iminosugars and calix[8]arene scaffolds differing in their va...