Suppression of circDcbld1 Alleviates Intimal Hyperplasia in Rat Carotid Artery by Targeting miR-145-3p/Neuropilin-1

• Autores principales: Zhi-Hua Rong (Autor), Neng-Bin Chang (Autor), Qing-Ping Yao (Autor), Tao Li (Autor), Xiao-Ling Zhu (Autor), Yu Cao (Autor), Mei-Jun Jiang (Autor), Yan-Shuang Cheng (Autor), Rui Jiang (Autor), Jun Jiang (Autor)
• Formato: Libro
• Publicado: Elsevier, 2019-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

We replicated the rat common carotid artery (CCA) intima hyperplasia model and found the expression of a circular RNA, circRNA_009723 (circDcbld1), was markedly increased in the CCA with intimal hyperplasia. In vitro, the suppression of circDcbld1 in rat vascular smooth muscle cells (VSMCs) led the...