Suppression of circDcbld1 Alleviates Intimal Hyperplasia in Rat Carotid Artery by Targeting miR-145-3p/Neuropilin-1

• Main Authors: Zhi-Hua Rong (Author), Neng-Bin Chang (Author), Qing-Ping Yao (Author), Tao Li (Author), Xiao-Ling Zhu (Author), Yu Cao (Author), Mei-Jun Jiang (Author), Yan-Shuang Cheng (Author), Rui Jiang (Author), Jun Jiang (Author)
• Format: Book
• Published: Elsevier, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We replicated the rat common carotid artery (CCA) intima hyperplasia model and found the expression of a circular RNA, circRNA_009723 (circDcbld1), was markedly increased in the CCA with intimal hyperplasia. In vitro, the suppression of circDcbld1 in rat vascular smooth muscle cells (VSMCs) led the...