Evaluation of HLA-G 14-bp ins/del and +3142G>C polymorphisms with susceptibility to recurrent spontaneous abortion

• Glavni autori: Mohammad Hashemi (Autor), Mojgan Mokhtari (Autor), Safura Khazaeian (Autor), Gholamreza Bahari (Autor), Maryam Rezaei (Autor), Alireza Nakhaee (Autor), Mohsen Taheri (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2017-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective: HLA-G is critically important for successful implantation during pregnancy. Increasing evidence supposed that HLA-G plays a key role in tolerance of the semi-allogeneic graft in pregnancy by inhibiting the cytotoxic functions of T and NK cells. The present study aimed to evaluate the impa...