Evaluation of HLA-G 14-bp ins/del and +3142G>C polymorphisms with susceptibility to recurrent spontaneous abortion

• Main Authors: Mohammad Hashemi (Author), Mojgan Mokhtari (Author), Safura Khazaeian (Author), Gholamreza Bahari (Author), Maryam Rezaei (Author), Alireza Nakhaee (Author), Mohsen Taheri (Author)
• Format: Book
• Published: Elsevier, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: HLA-G is critically important for successful implantation during pregnancy. Increasing evidence supposed that HLA-G plays a key role in tolerance of the semi-allogeneic graft in pregnancy by inhibiting the cytotoxic functions of T and NK cells. The present study aimed to evaluate the impa...