Evaluation of HLA-G 14-bp ins/del and +3142G>C polymorphisms with susceptibility to recurrent spontaneous abortion

• Главные авторы: Mohammad Hashemi (Автор), Mojgan Mokhtari (Автор), Safura Khazaeian (Автор), Gholamreza Bahari (Автор), Maryam Rezaei (Автор), Alireza Nakhaee (Автор), Mohsen Taheri (Автор)
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• Опубликовано: Elsevier, 2017-06-01T00:00:00Z.
• Предметы: article
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Objective: HLA-G is critically important for successful implantation during pregnancy. Increasing evidence supposed that HLA-G plays a key role in tolerance of the semi-allogeneic graft in pregnancy by inhibiting the cytotoxic functions of T and NK cells. The present study aimed to evaluate the impa...