Low Protective Efficacy of the Current Japanese Encephalitis Vaccine against the Emerging Genotype 5 Japanese Encephalitis Virus.

• मुख्य लेखकों: Lei Cao (लेखक), Shihong Fu (लेखक), Xiaoyan Gao (लेखक), Minghua Li (लेखक), Shiheng Cui (लेखक), Xiaolong Li (लेखक), Yuxi Cao (लेखक), Wenwen Lei (लेखक), Zhi Lu (लेखक), Ying He (लेखक), Huanyu Wang (लेखक), Jinghua Yan (लेखक), George Fu Gao (लेखक), Guodong Liang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The current Japanese encephalitis (JE) vaccine derived from G3 JE virus (JEV) can induce protective immunity against G1-G4 JEV genotypes. However, protective efficacy against the emerging G5 genotype has not been reported.Using in vitro and in vivo tests, biological phenotype and cross-immunoreactio...