Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats

• Hauptverfasser: Junke Song (Verfasst von), Wen Zhang (Verfasst von), Jialin Sun (Verfasst von), Xiaona Xu (Verfasst von), Xue Zhang (Verfasst von), Li Zhang (Verfasst von), Zhangying Feng (Verfasst von), Guan-hua Du (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2015-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

A sensitive, specific and rapid LC-MS method was developed and validated for the determination of salvianolic acid D (SalD) in rat plasma. This method used a single quadrupole mass spectrometer with an electrospray ionization (ESI) source. A single ion monitoring scanning (SIM) mode was employed. It...