Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats

• Main Authors: Junke Song (Author), Wen Zhang (Author), Jialin Sun (Author), Xiaona Xu (Author), Xue Zhang (Author), Li Zhang (Author), Zhangying Feng (Author), Guan-hua Du (Author)
• Format: Book
• Published: Elsevier, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A sensitive, specific and rapid LC-MS method was developed and validated for the determination of salvianolic acid D (SalD) in rat plasma. This method used a single quadrupole mass spectrometer with an electrospray ionization (ESI) source. A single ion monitoring scanning (SIM) mode was employed. It...