Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression

• Main Authors: Julia Rehnitz (Author), Birgitta Messmer (Author), Ulrike Bender (Author), Xuan Phuoc Nguyen (Author), Ariane Germeyer (Author), Katrin Hinderhofer (Author), Thomas Strowitzki (Author), Edison Capp (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 (FMR1) regulates folliculogenesis and it is variably expressed in patie...