Activation of AKT/mammalian target of rapamycin signaling in the peripheral blood of women with premature ovarian insufficiency and its correlation with FMR1 expression

• Главные авторы: Julia Rehnitz (Автор), Birgitta Messmer (Автор), Ulrike Bender (Автор), Xuan Phuoc Nguyen (Автор), Ariane Germeyer (Автор), Katrin Hinderhofer (Автор), Thomas Strowitzki (Автор), Edison Capp (Автор)
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• Опубликовано: BMC, 2022-03-01T00:00:00Z.
• Предметы: article
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Abstract Background The protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway regulates early follicular activation and follicular pool maintenance in female germline cells. Fragile X mental retardation 1 (FMR1) regulates folliculogenesis and it is variably expressed in patie...