C-Myc/H19/miR-29b axis downregulates nerve/glial (NG)2 expression in glioblastoma multiforme

• Автори: Anne S. Boewe (Автор), Selina Wrublewsky (Автор), Jessica Hoppstädter (Автор), Claudia Götz (Автор), Alexandra K. Kiemer (Автор), Michael D. Menger (Автор), Matthias W. Laschke (Автор), Emmanuel Ampofo (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2024-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Nerve/glial antigen (NG)2 is highly expressed in glioblastoma multiforme (GBM). However, the underlying mechanisms of its upregulated expression are largely unknown. In silico analyses reveal that the tumor-suppressive miR-29b targets NG2. We used GBM-based data from The Cancer Genome Atlas database...