C-Myc/H19/miR-29b axis downregulates nerve/glial (NG)2 expression in glioblastoma multiforme

• Main Authors: Anne S. Boewe (Author), Selina Wrublewsky (Author), Jessica Hoppstädter (Author), Claudia Götz (Author), Alexandra K. Kiemer (Author), Michael D. Menger (Author), Matthias W. Laschke (Author), Emmanuel Ampofo (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nerve/glial antigen (NG)2 is highly expressed in glioblastoma multiforme (GBM). However, the underlying mechanisms of its upregulated expression are largely unknown. In silico analyses reveal that the tumor-suppressive miR-29b targets NG2. We used GBM-based data from The Cancer Genome Atlas database...