Recent advances of sorafenib nanoformulations for cancer therapy: Smart nanosystem and combination therapy

• 主要な著者: Fangmin Chen (著者), Yifan Fang (著者), Xiang Chen (著者), Rui Deng (著者), Yongjie Zhang (著者), Jingwei Shao (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2021-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Sorafenib, a molecular targeted multi-kinase inhibitor, has received considerable interests in recent years due to its significant profiles of efficacy in cancer therapy. However, poor pharmacokinetic properties such as limited water solubility, rapid elimination and metabolism lead to low bioavaila...