The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7
The human voltage-gated sodium channel Nav1.7 is a widely proven target for analgesic drug studies. ProTx2, a 30-residue polypeptide from Peruvian green tarantula venom, shows high specificity to activity against human Nav1.7, suggesting its potential to become a non-addictive analgesic. However, it...
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Main Authors: | , , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2024-05-01T00:00:00Z.
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A1234.567 |
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