The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7

The human voltage-gated sodium channel Nav1.7 is a widely proven target for analgesic drug studies. ProTx2, a 30-residue polypeptide from Peruvian green tarantula venom, shows high specificity to activity against human Nav1.7, suggesting its potential to become a non-addictive analgesic. However, it...

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Main Authors: Fan Zhao (Author), Yuanyuan Liu (Author), Yiyu Liu (Author), Qi Ye (Author), Hongtao Yang (Author), Mingze Gui (Author), Yongbo Song (Author)
Format: Book
Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
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3rd Floor Main Library

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