Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity

• Main Authors: Xuemei Shi (Author), Shaji Chacko (Author), Feng Li (Author), Depei Li (Author), Douglas Burrin (Author), Lawrence Chan (Author), Xinfu Guan (Author)
• Format: Book
• Published: Elsevier, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Glucagon-like peptides are co-released from enteroendocrine L cells in the gut and preproglucagon (PPG) neurons in the brainstem. PPG-derived GLP-1/2 are probably key neuroendocrine signals for the control of energy balance and glucose homeostasis. The objective of this study was to deter...