Acute activation of GLP-1-expressing neurons promotes glucose homeostasis and insulin sensitivity

• Glavni autori: Xuemei Shi (Autor), Shaji Chacko (Autor), Feng Li (Autor), Depei Li (Autor), Douglas Burrin (Autor), Lawrence Chan (Autor), Xinfu Guan (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2017-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Objective: Glucagon-like peptides are co-released from enteroendocrine L cells in the gut and preproglucagon (PPG) neurons in the brainstem. PPG-derived GLP-1/2 are probably key neuroendocrine signals for the control of energy balance and glucose homeostasis. The objective of this study was to deter...