Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes.

• 主要な著者: Radoslaw P Kozak (著者), Karina Mondragon-Shem (著者), Christopher Williams (著者), Clair Rose (著者), Samirah Perally (著者), Guy Caljon (著者), Jan Van Den Abbeele (著者), Katherine Wongtrakul-Kish (著者), Richard A Gardner (著者), Daniel Spencer (著者), Michael J Lehane (著者), Álvaro Acosta-Serrano (著者)
• フォーマット: 図書
• 出版事項: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

African sleeping sickness is caused by Trypanosoma brucei, a parasite transmitted by the bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of tsetse genes encoding for salivary proteins, which reduces its anti-hemostatic and anti-clotting properties. To bett...