Leishmania-specific surface antigens show sub-genus sequence variation and immune recognition.

• Hauptverfasser: Daniel P Depledge (Verfasst von), Lorna M MacLean (Verfasst von), Michael R Hodgkinson (Verfasst von), Barbara A Smith (Verfasst von), Andrew P Jackson (Verfasst von), Saufung Ma (Verfasst von), Silvia R B Uliana (Verfasst von), Deborah F Smith (Verfasst von)
• Format: Buch
• Veröffentlicht: Public Library of Science (PLoS), 2010-09-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

A family of hydrophilic acylated surface (HASP) proteins, containing extensive and variant amino acid repeats, is expressed at the plasma membrane in infective extracellular (metacyclic) and intracellular (amastigote) stages of Old World Leishmania species. While HASPs are antigenic in the host and...