Thiopurines Induce Oxidative Stress in T-Lymphocytes: A Proteomic Approach

Thiopurines are extensively used immunosuppressants for the treatment of inflammatory bowel disease (IBD). The polymorphism of thiopurine S-methyltransferase (TPMT) influences thiopurine metabolism and therapy outcome. We used a TPMT knockdown (kd) model of human Jurkat T-lymphocytes cells to study...

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Main Authors: Misbah Misdaq (Author), Sonia Ziegler (Author), Nicolas von Ahsen (Author), Michael Oellerich (Author), Abdul R. Asif (Author)
Format: Book
Published: Hindawi Limited, 2015-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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