Whole-exome sequencing reveals potential mechanisms of drug resistance to FGFR3-TACC3 targeted therapy and subsequent drug selection: towards a personalized medicine

• मुख्य लेखकों: Zhou Tong (लेखक), Cong Yan (लेखक), Yu-An Dong (लेखक), Ming Yao (लेखक), Hangyu Zhang (लेखक), Lulu Liu (लेखक), Yi Zheng (लेखक), Peng Zhao (लेखक), Yimin Wang (लेखक), Weijia Fang (लेखक), Feifei Zhang (लेखक), Weiqin Jiang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Drug resistance is a major obstacle to effective cancer therapy. In order to detect the change in tumor genomic states under drug selection pressure, we use next-generation sequencing technology to investigate the underlying potential mechanisms of drug resistance. Methods In our...