2-Deoxystreptamine Conjugates by Truncation-Derivatization of Neomycin

• Egile Nagusiak: Floris L. van Delft (Egilea), Floris P.J.T. Rutjes (Egilea), Gerard W. Canters (Egilea), Alessio Andreoni (Egilea), Leandro C. Tabares (Egilea), M. Waqar Aslam (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2010-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization. The dimeric conjugates were evaluated for antibacterial activity w...