2-Deoxystreptamine Conjugates by Truncation-Derivatization of Neomycin

• Główni autorzy: Floris L. van Delft (Autor), Floris P.J.T. Rutjes (Autor), Gerard W. Canters (Autor), Alessio Andreoni (Autor), Leandro C. Tabares (Autor), M. Waqar Aslam (Autor)
• Format: Książka
• Wydane: MDPI AG, 2010-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

A small library of truncated neomycin-conjugates is prepared by consecutive removal of 2,6-diaminoglucose rings, oxidation-reductive amination of ribose, oxidation-conjugation of aminopyridine/aminoquinoline and finally dimerization. The dimeric conjugates were evaluated for antibacterial activity w...