Cathepsin D is essential for the degradomic shift of macrophages required to resolve liver fibrosis

• প্রধান লেখক: Paloma Ruiz-Blázquez (লেখক), María Fernández-Fernández (লেখক), Valeria Pistorio (লেখক), Celia Martinez-Sanchez (লেখক), Michele Costanzo (লেখক), Paula Iruzubieta (লেখক), Ekaterina Zhuravleva (লেখক), Júlia Cacho-Pujol (লেখক), Silvia Ariño (লেখক), Alejandro Del Castillo-Cruz (লেখক), Susana Núñez (লেখক), Jesper B. Andersen (লেখক), Margherita Ruoppolo (লেখক), Javier Crespo (লেখক), Carmen García-Ruiz (লেখক), Luigi Michele Pavone (লেখক), Thomas Reinheckel (লেখক), Pau Sancho-Bru (লেখক), Mar Coll (লেখক), José C. Fernández-Checa (লেখক), Anna Moles (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2024-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background and objectives: Fibrosis contributes to 45% of deaths in industrialized nations and is characterized by an abnormal accumulation of extracellular matrix (ECM). There are no specific anti-fibrotic treatments for liver fibrosis, and previous unsuccessful attempts at drug development have fo...