Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents

• 主要な著者: Juliusz Maksymilian Walczak (著者), Dorota Iwaszkiewicz-Grześ (著者), Michalina Ziomkowska (著者), Magdalena Śliwka-Kaszyńska (著者), Mateusz Daśko (著者), Piotr Trzonkowski (著者), Grzegorz Cholewiński (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The group of 18 new amide derivatives of mycophenolic acid (MPA) and selected heterocyclic amines was synthesised as potential immunosuppressive agents functioning as inosine-5'-monophosphate dehydrogenase (IMPDH) uncompetitive inhibitors. The synthesis of 14 of them employed uronium-type activ...