Targeting Phosphorylation of p21-activated Kinase 1 at Thr423 Induces Cell Cycle Arrest and Apoptosis in Cutaneous T-cell Lymphoma Cells
Cutaneous T-cell lymphoma (CTCL) represents a rare group of extranodal T-cell lymphoproliferative diseases. Due to poor clinical outcome of CTCL, there is an urgent need for new and improved therapies. A small molecule, IPA-3, which inhibits p21-activated kinase 1 (PAK1), has shown therapeutic poten...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Medical Journals Sweden,
2019-08-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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